A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Patel, Kiran M.
- Mosquito Sting:A Host of Parasites and Virions
Authors
1 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Gujarat Technological University, Arvind Baug, Mehsana-384001, Gujarat, IN
Source
Research Journal of Science and Technology, Vol 3, No 3 (2011), Pagination: 119-126Abstract
Mosquitoes are a vector agent that carries mosquito-borne disease, transmitting viruses and parasites from person to person without catching the disease themselves. Mosquitoes carrying these viruses stay healthy while carrying them because their immune system recognizes them as bad and "chops off" the virus's genetic coding, rendering it harmless. It is currently unknown how they handle parasites so they can safely carry them. Infection of humans occurs when a mosquito bites someone while its immune system is still in the process of destroying the virus's harmful coding. Female mosquitoes suck blood from people and other animals as part of their eating and breeding habits. Mosquito borne diseases are prevalent in more than 100 countries, infecting 300-500 million people and causing about 1 million deaths every year. In India, more than 40 million people suffer from mosquito diseases annually. There are a number of diseases borne by mosquitoes. They are malaria, filaria, dengue, brain fever and yellow fever. Yellow fever is caused by mosquitoes in jungle areas in parts of Africa and South America. In India, malaria, filaria and dengue are the most prevalent diseases spread by mosquitoes. The diseases continue to explode from time to time. The reason is that these mosquitoes develop resistance to medicines and chemicals. Hence fighting mosquitoes and the diseases spread by them is a continuous process.Keywords
Virus Genetic Code, Malaria, Encephalitis, Filarial, Dengue, Brain Fever, Yellow Fever, Drug Resistance.
- Latest Strategy of Medicinal Chemistry Implements In-silico After In-Vivo and In-Vitro
Authors
1 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana- 384001, Gujarat, IN
2 Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Hemchandracharya North Gujarat University, Arvind Baug, Mehsana- 384001, Gujarat, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 2 (2011), Pagination: 167-180Abstract
The inner eye of chemistry looks forward to the biology for getting the best output to design a potent drug molecule after crossing the iron gates of pharmacological as well as clinical trials. The basic scientific research in pharmacy is blooming in the impact of the compatibility of designed chemical molecule towards biological molecule. Latest technology in pharmaceutical science reflects the implementation of new methodologies to screen a new chemical entity in a biological system. The inner eye of chemistry looks forward to the biology for getting the best output to design a potent drug molecule after crossing the iron gates of pharmacological as well as clinical trials. The basic scientific research in pharmacy is blooming in the impact of the compatibility of designed chemical molecule towards biological molecule. Latest technology in pharmaceutical science reflects the implementation of new methodologies to screen a new chemical entity in a biological system. A representative problem in bioinformatics is the assembly of high-quality genome sequences from fragmentary "shotgun" DNA sequencing. Other common problems include the study of gene to perform expression profiling using data from microarrays or mass spectrometry. Framing the structural framework of a chemical molecule is first done by in-silico by computational chemistry and that is synthesized by in-situ method. This after synthesis the biological screening is done by both in-vitro and in-vivo studies to enlist as a potent moiety by QSAR. All these newer techniques possess a prefix “In” for in-vitro, in-vivo, in-situ and in-silico which are the In-ner eye of the members of pharmaceutical research.